activating transcription factors造句

• FAM83A shows decreased expression when activating transcription factor 2 ( ATF2 ) is knocked out.
• CDK6 is involved in a positive feedback loop that activates transcription factors through a reaction cascade.
• RUVBL2 has been shown to interact with RuvB-like 1 and Activating transcription factor 2.
• This calcium then interacts with calcineurin and calcium / calmodulin-dependent kinases that in turn activate transcription factors.
• This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP ( basic-region leucine zipper ) family.
• Several signaling pathways ( TGF-beta, nuclear factor-kappaB and Activating Transcription Factor 2 have been implicated to be involved in EMT.
• GATA-1 serves as an activating transcription factor of Cyclin D and potentially also as a repressor of the Cyclin D inhibitor, p16.
• Nuclear receptors are ligand-activated transcription factors involved in the regulation of many processes, including development, reproduction and homologue KSHV IRF-1.
• Activating transcription factor 3 is a member of the mammalian activation transcription factor / cAMP responsive element-binding ( CREB ) protein family of transcription factors.
• CREB is closely related in structure and function to CREM ( cAMP response element modulator ) and ATF-1 ( activating transcription factor-1 ) proteins.
• The mainly positively charged surface of NFKBID close to DNA blocks the exchange of the p50 / p50 dimer with other dimers, that are activating transcription factors.
• The JAK autophosphorylation induces a conformational change within itself, enabling it to transduce the intracellular signal by further phosphorylating and activating transcription factors called transcription of selected genes.
• These molecules are translocated in the nucleus, where they induce IFN production with the presence of C-Jun ( a particular transcription factor ) and activating transcription factor 2.
• First described by Nishizawa and Nagata, ATF5 has been classified as a member of the activating transcription factor ( ATF ) / cAMP response-element binding protein ( CREB ) family.
• Low molecular weight PAHs that have bay or bay-like regions can dysregulate gap junction channels, interfering with intercellular communication, and also affect mitogen-activated protein kinases that activate transcription factors involved in cell proliferation.
• An important example is that the proapoptotic protein CHOP ( CCAAT /-enhancer-binding protein homologous protein ), is upregulated downstream of the bZIP transcription factor ATF4 ( activating transcription factor 4 ) and uniquely responsive to ER stress 15.
• The amino acid response pathway is triggered by shortage of any essential amino acid, and results in an increase in activating transcription factor ATF4, which in turn affect many process by sundry pathways to limit or increase the production of other proteins.
• Contraction-induced changes in intracellular calcium or reactive oxygen species provide signals to diverse pathways that include the MAPKs, calcineurin and calcium / calmodulin-dependent protein kinase IV to activate transcription factors that regulate gene expression and enzyme activity in skeletal muscle.
• Data from patients suggest that aberrant levels of activating transcription factor in the nucleus of melanoma cells are associated with increased metastatic activity of melanoma cells; studies from mice on skin cancer tend to confirm a role for activating transcription factor-2 in cancer progression.
• Data from patients suggest that aberrant levels of activating transcription factor in the nucleus of melanoma cells are associated with increased metastatic activity of melanoma cells; studies from mice on skin cancer tend to confirm a role for activating transcription factor-2 in cancer progression.